منابع مشابه
Gene-environment Interaction: The Causes of High Obesity Incidence.
Urbanization has provided experimental settings for testing the interactive relationship between genetic background and changes in lifestyle and dietary patterns. The concept of gene-environment interaction was described by epidemic of obesity along with urbanization. Genome-wide association has identified several genes such as melanocortin-4 receptor that associates with environmental influenc...
متن کاملA Gene-Environment Interaction
Background—Particulate air pollution has been associated with cardiovascular mortality and morbidity. Transition metals such as iron bound to the particles may be responsible for those associations. The protein product of the hemochromatosis (HFE) gene modulates uptake of iron and divalent cations from pulmonary sources and reduces their toxicity. Two HFE polymorphisms (C282Y and H63D) associat...
متن کاملFrom Genotype × Environment Interaction to Gene × Environment Interaction
Historically in plant breeding a large number of statistical models has been developed and used for studying genotype × environment interaction. These models have helped plant breeders to assess the stability of economically important traits and to predict the performance of newly developed genotypes evaluated under varying environmental conditions. In the last decade, the use of relatively low...
متن کاملGene–Environment Interaction in Yeast Gene Expression
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood. Recently developed approaches that treat transcript abundances of thousands of genes as quantitative traits offer the opportunity to broadly characterize the architecture of gene-environment interactions. We examined the g...
متن کاملModerate alcohol consumption, dietary fat composition, and abdominal obesity in women: evidence for gene-environment interaction.
We examined relationships among alcohol intake, dietary fat composition, and total body fat (TBF) and central abdominal fat (CAF), independent of genetic confounders, and evaluated the modulating effect of genetic susceptibility. We studied 334 female twins (57.7 +/- 6.7 yr) after excluding dietary underreporters. Diet was assessed by Food-Frequency Questionnaire and body fat by dual-energy x-r...
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ژورنال
عنوان ژورنال: Nutrition Reviews
سال: 2008
ISSN: 0029-6643
DOI: 10.1111/j.1753-4887.2008.00128.x