GENE DOSAGE AND GALACTOSE UTILIZATION BY SACCHAROMYCES TETRAPLOIDS
نویسندگان
چکیده
منابع مشابه
Gene Dosage and Galactose Utilization by Saccharomyces Tetraploids.
In yeast, the enzymes required for steps (1) to ( 3 ) are “induced” enzymes which are synthesized only if galactose is present in the medium (DE ROBICHONSZULMAJSTER 1958). The nonallelic genes GA, and GA, are required in our strains of Saccharomyces for the rapid fermentation of galactose. GA, appears to control the transfer of galactose into the cell (DOUGLAS and CONDIE 1954) ; in the absence ...
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The gal3 mutation of Saccharomyces, which is associated with an impairment in the utilization of galactose, has been shown to be pleiotropic, causing similar impairments in the utilization of melibiose and maltose. Milibiose utilization and alpha-galactosidase production are directly controlled by the galactose regulatory elements i, c, and GAL4. The fermentation of maltose and the induction of...
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Accumulation of galactose in dairy products due to partial lactose fermentation by lactic acid bacteria yields poor-quality products and precludes their consumption by individuals suffering from galactosemia. This study aimed at extending our knowledge of galactose metabolism in Lactococcus lactis, with the final goal of tailoring strains for enhanced galactose consumption. We used directed gen...
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Mutations in our breeding stocks of Saccharomyces that produce the galactosenegative phenotype by blocking specific steps in this reaction sequence are gal, which affects the activity of galactokinase ( ROBICHON-SZULMAJSTER 1958) and gu,, which affects the activity of phosphoglucomutase (DOUGLAS 1961). Other mutations also affect the galactose phenotype of yeast. The transport of galactose into...
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The evolutionary process leading to the fixation of newly duplicated genes is not well understood. It was recently proposed that the fixation of duplicate genes is frequently driven by positive selection for increased gene dosage (i.e., the gene dosage hypothesis), because haploinsufficient genes were reported to have more paralogs than haplosufficient genes in the human genome. However, the pr...
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ژورنال
عنوان ژورنال: Genetics
سال: 1963
ISSN: 1943-2631
DOI: 10.1093/genetics/48.12.1585