منابع مشابه
The PTP Family Photo Album
Protein tyrosine phosphatases (PTPs) are central players in many biological processes. In this issue, Barr et al. (2009) analyze 22 different PTP structures to define their common and unique features. This effort provides key insights into the regulation of PTP activity that could lead to the development of new therapeutics.
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Digital photographs are replacing tradition films in our daily life and the quantity is exploding. This stimulates the strong need for efficient management tools, in which the annotation of “who” in each photo is essential. In this paper, we propose an automated method to annotate family photos using evidence from face, body and context information. Face recognition is the first consideration. ...
متن کاملReconstruction and Analysis of Gene Family Evolution in Mammals
Gene duplication and loss is a dynamic and ongoing process during evolution and both play a significant role in the rise of variable size gene families originating from a single ancestral gene. Recreating the evolutionary history of these gene families is an important goal of contemporary comparative genomics as understanding gene family histories can reveal many of the evolutionary forces acti...
متن کاملMolecular Evolution of the TET Gene Family in Mammals
Ten-eleven translocation (TET) proteins, a family of Fe(2+)- and 2-oxoglutarate-dependent dioxygenases, are involved in DNA demethylation. They also help regulate various cellular functions. Three TET paralogs have been identified (TET1, TET2, and TET3) in humans. This study focuses on the evolution of mammalian TET genes. Distinct patterns in TET1 and TET2 vs. TET3 were revealed by codon-based...
متن کاملFamily Proteins in Mammals
DNA damage causes chromosomal instability leading to oncogenesis, apoptosis, and severe failure of cell functions. The DNA repair system includes base excision repair, nucleotide excision repair, mismatch repair, translesion replication, non-homologous end-joining, and recombinational repair. Homologous recombination performs the recombinational repair. The gene is an ortholog of , and the gene...
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ژورنال
عنوان ژورنال: Nature
سال: 2000
ISSN: 0028-0836,1476-4687
DOI: 10.1038/35012773