Gender Difference in Type 1 Diabetes: An Underevaluated Dimension of the Disease

Gender difference in all fields of medicine and biology has recently become a topic great interest. At present, most studies report gender differences their secondary analysis; however, this information receives scant attention from clinicians, is often overwhelmed by press trumpeting the overall main positive results. Furthermore, more importantly, any statistical evaluation results obtained without specific careful planning study for research probably worthless. There are few animals, but these not typically useful because different biology, pharmacodynamics pharmacokinetics compared to humans. Type 1 diabetes disease where can be easily evaluated. Irrespective cause loss pancreatic beta-cell function, common denominators forms type absence circulating insulin reduction peripheral sensitivity leading exogenous injections being required. Consequently, infusion, with widely used tools, such as insulin–glucose clamp, evaluate difference. Female patients have many factors that impact glucose level. For example, hormones drive ovulatory/menstrual cycle connected change at time menopause role on action; thus, one should expect emphasis this. On contrary, there dearth data available topic, no pump producer created gender-specific infusion profile. Patients usually approached basis diagnosis. This review intended focus personalized treatment, specifically gender, according modern way thinking.