GC/MS Screening Method for Phthalate Esters in Children's Toys
نویسندگان
چکیده
منابع مشابه
Exposure to phthalate esters.
The American Chemistry Council Phthalate Esters Panel read with great interest the paper by Blount et al. (1) regarding urinary levels of phthalate ester metabolites in a sample set of the Third National Health and Nutrition Examination Survey (NHANES III) population. We have known for some time of this research, and have provided whatever information and assistance we could to the Centers for ...
متن کاملHigh Performance Liquid Chromatographic (HPLC) Method for Comparison of Levels of some Phthalate Esters in Children’s Toys and Their Health Implications
The phthalate esters contents of children toys were analyzed using High Performance Liquid Chromatography (HPLC). Understanding the distribution of ubiquitous phthalate esters in plastic products were necessary because of their subtle toxicity to humans. The phthalate esters were obtained using liquid-liquid extraction procedure, after which the extracts were cleaned up using solid phase clean ...
متن کاملTesticular effects of phthalate esters.
The testicular effects produced by di(2-ethylhexyl) phthalate (DEHP) in the rat, characterized by a decrease in the relative organ weight and histological changes in the seminiferous tubules, can also be produced by di-n-butyl, di-n-pentyl and di-n-hexyl phthalates. The corresponding monoesters of these compounds, formed in vivo as a result of the action of nonspecific esterases in the intestin...
متن کاملMitochondrial toxicity of phthalate esters.
The effects of mono- and dibutyl phthalate and mono- and di(2-ethylhexyl) phthalate on energy-dependent K+ uptake, respiration rates, and succinate cytochrome c reductase activities of isolated rat liver mitochondria were evaluated. The energy-coupling processes, active K+ transport and oxidative phosphorylation, were affected most by di-n-butyl phthalate and mono(2-ethylhexyl) phthalate. Mono-...
متن کاملHepatic effects of phthalate esters.
Di(2-ethylhexyl) phthalate (DEHP), a commonly used plasticizer and microchemical environmental pollutant, produces subtle changes in hepatic function as judged by increase in liver weight and morphological and biochemical alterations. It can modify the biological response of drugs and other xenobiotics. Such interactions appear to occur at the pharmacokinetic phase, as DEHP was found to alter t...
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ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 2009
ISSN: 1060-3271,1944-7922
DOI: 10.1093/jaoac/92.3.951