GATA2 −/− human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment
نویسندگان
چکیده
منابع مشابه
Intra-Aortic Clusters Undergo Endothelial to Hematopoietic Phenotypic Transition during Early Embryogenesis
Intra-aortic clusters (IACs) attach to floor of large arteries and are considered to have recently acquired hematopoietic stem cell (HSC)-potential in vertebrate early mid-gestation embryos. The formation and function of IACs is poorly understood. To address this issue, IACs were characterized by immunohistochemistry and flow cytometry in mouse embryos. Immunohistochemical analysis revealed tha...
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ژورنال
عنوان ژورنال: Cell Regeneration
سال: 2015
ISSN: 2045-9769
DOI: 10.1186/s13619-015-0018-7