Gastroprotective Effect of Tabernaemontana divaricata (Linn.) R.Br. Flower Methanolic Extract in Wistar Rats

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منابع مشابه

Prostaglandin Analogous and Antioxidant Activity Mediated Gastroprotective Action of Tabernaemontana divaricata (L.) R. Br. Flower Methanolic Extract against Chemically Induced Gastric Ulcers in Rats

The present study was conducted to evaluate the antiulcerogenic effect and recognize the basic mechanism of action of Tabernaemontana divaricata (L.) R. Br. flowers. T. divaricata flower methanolic extract (TDFME) was screened for antiulcer activity versus aspirin and ethanol induced gastric ulcers at three doses--125, 250, and 500 mg/kg--orally using misoprostol as a standard. Besides histopat...

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Analgesic and Anti-inflammatory Effect of Ethanolic Extract of Tabernaemontana divaricata L. Flowers in Rats

Ethanolic extract of Tabernaemontana divaricata L. (TD) flowers were evaluated for analgesic and antiinflammatory effects on Wistar rat model. Analgesic and anti-inflammatory potential of TD flowers at doses of 125, 250 & 500 mg/kg was evaluated against the standard drug indomethacin at a dose of 20 mg/kg, p.o. Wistar rats of either sex of 6 numbers in each group was undertaken for study and ev...

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ANXIOLYTIC ACTIVITY OF TABERNAEMONTANA DIVARICATA (LINN) R. Br. FLOWERS EXTRACT IN MICE

The present study was undertaken to evaluate anxiolytic activity of alcoholic flowers extract of Tabernaemontana divaricata (Linn) R.Br. (ALETD) by using mice. This plant contains carbohydrates, steroids, tannins, triterpenes, flavonoids, proteins, amino acids and glycosides. Anxiolytic effect of ALETD (100, 200 and 400 mg/kg) was studied and diazepam used as a standard drug by using following ...

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the effect of aqueous extract of garlic on formalin-induced pain in male rats

چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...

15 صفحه اول

Tabernaemontana divaricata leaves extract exacerbate burying behavior in mice

OBJECTIVE Tabernaemontana divaricata (TD) from Apocynaceae family offers the traditional folklore medicinal benefits such as an anti-epileptic, anti-mania, brain tonic, and anti-oxidant. The aim of the present study was to evaluate the effect of ethanolic extract of TD leaves on burying behavior in mice. MATERIALS AND METHODS Mice were treated with oral administration (p.o.) of ethanolic extr...

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ژورنال

عنوان ژورنال: British Journal of Pharmaceutical Research

سال: 2011

ISSN: 2231-2919

DOI: 10.9734/bjpr/2011/347