Gastroprotective and Antioxidant Effects of Montelukast on Indomethacin-Induced Gastric Ulcer in Rats
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چکیده
منابع مشابه
Gastroprotective effect of sodium hydrosulfide against indomethacin-induced gastric ulcer in diabetic rats
Introduction: The incidence rate of gastric erosions and ulcers in diabetic patients are higher due to failure of mucosal antioxidant defense and maintain enough blood flow. The present study evaluated the gastro-protective effect of sodium hydrosulfide (NaHS) against indomethacin-induced gastric lesions in diabetic rats. Methods: In order to test anti-ulcer activity of NaHS against indomet...
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Objective: Zataria multiflora has been reported to have several medicinal properties including antioxidant, antibacterial, antispasmodic, and expectorant activities. This study aimed to investigate the effect of Z. multiflora hydro-alcoholic extract (ZMHE) on peptic ulcer caused by indomethacin in rats. Materials and Methods: ZMHE was prepared by maceration, condensed by rotary evaporator and ...
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This study investigated the gastroprotective effect of Lcarnitine against indomethacin-induced gastric ulcer in rats and the possible mechanisms underlying this effect. Two sets of experiments were performed. In the first set male albino rats (170-210 g) were randomly allocated into a normal control group, ulcer control group (received a single dose of indomethacin 30 mg/kg po) and three ulcer ...
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Tricyclic antidepressants are particularly useful in the treatment of endogenous depression. Since the 1950s, tricyclic antidepressants (TCAs) have also been used for the treatment of gastric ulcer disease. Many TCAs have been evaluated for their antiulcer effects, but there are presently no data in the literature specifically concerning the antidepressant opipramol. This study aimed to investi...
متن کاملGastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats
BACKGROUND Gastric peptic ulcer is one of the common disorders of gastrointestinal tract, which occur due to an imbalance between the offensive and defensive factors. It is an illness that affects a considerable number of people worldwide. This study was conducted to evaluate the antiulcerogenic and antiulcer effects and recognize the basic mechanism of action of Piptadeniastrum africanum stem ...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2007
ISSN: 1347-8613,1347-8648
DOI: 10.1254/jphs.fp0070122