Gastrointestinal Stromal Tumors: Recurrence and Survival Analysis of 49 Patients

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor originating from gastrointestinal tract and have a broad spectrum of clinicopathological features affecting disease management regarding treatment modalities. Methods: A retrospective study 49 patients who underwent surgery for between 2008 2016 was conducted. Clinical, pathological, immunohistochemical with without recurrence were statistically analyzed.Results: Twenty-nine (59.1%) had gastric; 16 (32.6%) small intestinal; 3 (6.1%) mesenteric; 1 (2.2%) rectal GISTs. Microscopic necrosis ulceration also significant (P = 0.005, P 0.049). High-risk according to Miettinen’s risk classification more likely develop < 0.001). Additionally, high-grade factor Ki-67 levels available in 40 mean level 16.8 recurrence, which regression analysis (HR: 1.24, 95%, CI: 1.08-1-43). Five-year disease-free survival rates non-gastric gastric GISTs 62.3% 90%, respectively 0.044).Conclusion: Larger higher mitotic recurrence. High associated