Gastrointestinal stress as innate defence against microbial attack

Defensins and innate host defence of the gastrointestinal tract.

Between microbial attack and defence: the endothelium as a vulnerable player in infectious diseases.

Thromb Haemost 2009; 102: 1011–1013 The majority of death-related pathologies worldwide are related directly or indirectly to infectious diseases, and a large variety of invasive mechanisms by which viruses, bacteria and parasites enter our body and also gain access to the vascular system have been identified. Prominent examples are virus-induced haemorrhagic fevers, bacteraemia followed by sep...

A Nobel Defence Scheme Against Selfish Node Attack in MANET

Security is one of the major issue in wired and wireless network but due to the presence of centralized administration not difficult to find out misbehavior in network other than in Mobile Ad hoc Network due to the absence of centralized management and frequently changes in topology security is one of a major issue in MANET. Only prevention methods for attack are not enough. In this paper a new...

Innate Immune Defence to

Campylobacter jejuni is the most prevalent cause of bacterial diarrhoea worldwide and is frequently associated with severe post-infectious complications such as the GuillainBarre syndrome. Despite the serious health burden caused by the bacterium disease pathogenesis remains ill defined. Human (3-defensins (hBDs), a family of epithelial antimicrobial peptides, are a major component of host inna...

Autophagy as a defence against intracellular pathogens.

Autophagy is a membrane trafficking pathway that results in the formation of autophagosomes which deliver portions of the cytosol to lysosomes for degradation. When autophagosomes engulf intracellular pathogens, the pathway is called 'xenophagy' because it leads to the removal of foreign material. Autophagy is activated during infection by Toll-like receptors that recognize pathogen-associated ...