منابع مشابه
Mucins in Gastric Cancer - An Update.
Mucins are high-molecular-weight glycoproteins expressed throughout the gastrointestinal tract, with a key role in mucosal protection and function. In gastric cancer expression of MUC5AC and MUC1 is reduced and denovo expression of MUC2 occurs. With progressive loss of tumor differentiation and increased tumor stage, expression of MUC5AC and MUC1 is further reduced, and MUC2 decreases. Isolated...
متن کاملCancer Stem Cell Markers CD44, CD133 in Primary Gastric Adenocarcinoma
Cancer stem cells (CSCs) are unique subpopulations that have the capacity to drive malignant progression with renewal abilities. Recently the role of some of CSCs in gastric adenocarcinoma has been studied. This study was performed in order to evaluate CD44 and CD133 expressions by immunohistochemistry in 95 primary gastric adenocarcinoma and their relation to clinical and pathological paramete...
متن کاملClinical and biological markers in gastric cancer: update and perspectives.
Gastric cancer is the second cause of death from cancer worldwide and the only chance to reach better outcomes lays on an early diagnosis. The need for non-invasive, low-cost tests is invoked also in countries in which imaging and endoscopic screening have already showed the ability to improve early diagnosis and overall survival. Genomic medicine could allow a better understanding of regulator...
متن کاملRecurrent Venous Thromboembolism as the Initial Clinical Presentation of Gastric Cancer: A Case Report
Pulmonary thromboembolism (PTE) is a clinically critical disease, misdiagnosis or delayed diagnosis of which can lead to increased rate of mortality. For prevention of recurrence of PTE, recognition of its risk factors or underlying diseases is of great importance. PTE is common in patients with cancer and has high morbidity and mortality rates. Although cancer is a lethal condition, PTE accele...
متن کاملImmunohistochemical Profile of Mucins in Gastric Carcinoma
Gastric cancer represents the second leading cause of cancer related death (after lung cancer) despite a global decline in both its incidence and mortality since the late half of the 20th century (Kelley & Duggan, 2003; Zheng et al., 2008). This type of cancer continues nowadays to be a major health problem due to the slow decrease in incidence in Asia and its high mortality in the western coun...
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ژورنال
عنوان ژورنال: Gut
سال: 1992
ISSN: 0017-5749
DOI: 10.1136/gut.33.12.1681