Gap junctional communication in human osteoclastsin vitroandin vivo
نویسندگان
چکیده
منابع مشابه
Gap junctional communication in human osteoclasts in vitro and in vivo
Bone-forming cells are known to be coupled by gap junctions, formed primarily by connexin43 (Cx43). The role of Cx43 in osteoclasts has so far only been studied in rodents, where Cx43 is important for fusion of mononuclear precursors to osteoclasts. Given the potential importance for human diseases with pathologically altered osteoclasts, we asked whether a similar influence of Cx43 can also be...
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Astaxanthin is a carotenoid found in plants and algae; it provides the color of marine seafood such as salmon, lobster, or shrimp. Carotenoids are antioxidants and exhibit other biological functions, including effects on gap junctional communication important for homeostasis, growth control, and development of cells. Cancer cells have an impaired gap junctional intercellular communication. The ...
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Gap junctions (GJ) provide intercellular communication in all multicellular animal species, being as evolutionary distant as worm and men. In the traditional view GJs are known as specialized cell junctions forming communicating channels connecting the cytoplasm of adjacent cells. In almost all tissues GJ coupled cells can rapidly exchange ions, nutrients, or small metabolites to establish elec...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2008
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2008.00275.x