Gamma Knife Thalamotomy for Disabling Tremor

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Gamma knife thalamotomy for disabling tremor: a blinded evaluation.

BACKGROUND Gamma knife thalamotomy (GKT) has been used as a therapeutic option for patients with disabling tremor refractory to medications. Impressive improvement of tremor has been reported in the neurosurgical literature, but the reliability of such data has been questioned. OBJECTIVE To prospectively evaluate clinical outcomes after GKT for disabling tremor with blinded assessments. DES...

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A prospective single-blind study of Gamma Knife thalamotomy for tremor.

OBJECTIVE To evaluate the safety and efficacy of unilateral Gamma Knife thalamotomy (GKT) for treatment of severe tremor with a prospective blinded assessment. METHODS Fifty patients (mean age: 74.5 years; 32 men) with severe refractory tremor (36 essential, 14 parkinsonian) were treated with unilateral GKT. Targeting of the ventral intermediate nucleus (Vim) was achieved with Leksell Gamma K...

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Gamma Knife thalamotomy for tremor in the magnetic resonance imaging era.

OBJECT The surgical management of disabling tremor has gained renewed vigor with the availability of deep brain stimulation. However, in the face of an aging population of patients with increasing surgical comorbidities, noninvasive approaches for tremor management are needed. The authors' purpose was to study the technique and results of stereotactic radiosurgery performed in the era of MRI ta...

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Outcome of Gamma Knife Thalamotomy in Patients with an Intractable Tremor

OBJECTIVE Tremor is a common movement disorder that interferes with daily living. Since the medication for tremor has some limitations, surgical intervention is needed in many patients. In certain patients who cannot undergo aggressive surgical intervention, Gamma Knife thalamotomy (GKT) is a safe and effective alternative. METHODS From June 2012 to August 2013, 7 patients with an intractable...

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Multi-Institutional Outcome Analysis of Gamma Knife Radiosurgery for Tremor

Tremor is the most common movement disorder, with more than five million Americans affected. Tremor reduces overall quality of life, most notably by impairing employment, daily tasks, and taking a psychological toll. Unfortunately, many patients do not respond to medical therapy. Deep-brain stimulation (DBS) and radiofrequency thalamotomy (RFT) are invasive procedures that ablate the ventralis ...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2010

ISSN: 0003-9942

DOI: 10.1001/archneurol.2010.69