Gadd45a levels in human breast cancer are hormone receptor dependent
نویسندگان
چکیده
منابع مشابه
Steroidal Hormone Receptor Expression in Male Breast Cancer
Introduction: The etiology of male breast cancer is unclear, but hormonal levels may play a role in development of this disease. It seems that the risk of male breast cancer related to increased lifelong exposure to estrogen or reduced androgen. The aim of this study was to investigate the expression of the steroid hormone receptors including estrogen receptor (ER) and progesterone receptor (PR...
متن کاملsteroidal hormone receptor expression in male breast cancer
introduction: the etiology of male breast cancer is unclear, but hormonal levels may play a role in development of this disease. it seems that the risk of male breast cancer related to increased lifelong exposure to estrogen or reduced androgen. the aim of this study was to investigate the expression of the steroid hormone receptors including estrogen receptor (er) and progesterone receptor (pr...
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BRCA1 mRNA and protein levels are regulated by the steroid hormones estrogen and progesterone in human breast cancer cells. BRCA1 mRNA and protein levels were significantly decreased in estrogen-depleted MCF-7 and BT20T cells and increased again after stimulation with beta-estradiol. The increase in BRCA1 expression upon stimulation with estrogen was not coordinated with the early induction of ...
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BRCA1 mRNA and protein levels are regulated by the steroid hor monesestrogenand progesteronein humanbreastcancercells. BRCA1 mRNA and protein levels were significantly decreased in estrogen-de pleted MCF-7 and BT2OT cells and increased again after stimulation with @3-estradiol. The increase in BRCA1 expression upon stimulation with estrogen was not coordinated with the early induction of the es...
متن کاملSex Hormone Receptor Repertoire in Breast Cancer
Classification of breast cancer as endocrine sensitive, hormone dependent, or estrogen receptor (ER) positive refers singularly to ER α . One of the oldest recognized tumor targets, disruption of ER α -mediated signaling, is believed to be the mechanistic mode of action for all hormonal interventions used in treating this disease. Whereas ER α is widely accepted as the single most important pre...
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ژورنال
عنوان ژورنال: Journal of Translational Medicine
سال: 2013
ISSN: 1479-5876
DOI: 10.1186/1479-5876-11-131