GABARAPL1 Promotes AR+ Prostate Cancer Growth by Increasing FL-AR/AR-V Transcription Activity and Nuclear Translocation
نویسندگان
چکیده
منابع مشابه
ING3 promotes prostate cancer growth by activating the androgen receptor
BACKGROUND The androgen receptor (AR) is a major driver of prostate cancer, and increased AR levels and co-activators of the receptor promote the development of prostate cancer. INhibitor of Growth (ING) proteins target lysine acetyltransferase or lysine deacetylase complexes to the histone H3K4Me3 mark of active transcription, to affect chromatin structure and gene expression. ING3 is a stoich...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2019
ISSN: 2234-943X
DOI: 10.3389/fonc.2019.01254