منابع مشابه
G6PD deficiency.
T HIRTY-FIVE YEARS ago Dr William Dameshek, the first editor of the emerging journal Blood, invited me to write a review on “The Hemolytic Effect of Primaquine.”’ At the time, primaquine sensitivity, which had just recently been shown to be caused by a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD); represented a unique example of an inherited deficiency of an enzyme that cau...
متن کاملEvaluation of G6PD Deficiency in Acne Patients
Introduction: Various factors are involved in the pathogenesis of acne vulgaris. Recently, G6PD deficiency has been proposed in the pathogenesis of acne. G6PD has an important role in the oxidant/antioxidant balance. According to this theory, antioxidants are used in the treatment of acne recently. The aim of this study was to evaluate G6PD deficiency in patient with acne vulgaris. Methods: The...
متن کاملModelling primaquine-induced haemolysis in G6PD deficiency
Primaquine is the only drug available to prevent relapse in vivax malaria. The main adverse effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd). As testing for G6PDd is often unavailable, this limits the use of primaquine for radical cure. A compartmental model of the dynamics of red blood c...
متن کاملPrevalence of G6PD Deficiency in Iran
LETTER TO ETITOR G6PD (Glucose-6-Phosphate Dehydrogenase) enzyme deficiency is the most common inherited enzyme deficiency so far reported. 1 This enzyme deficiency affects 400 million people worldwide. 2 Most cases of the disease are from tropical regions of Africa, the Middle East, tropical and subtropical regions of Asia and the Mediterranean margin, arise from the process of natural selecti...
متن کاملStudy of erythrocyte G6PD deficiency in leprosy.
A survey of a number of ethnic groups in the Mediterranean region, Middle East and Africa has demonstrated that the pattern of distribution of G6PD deficiency roughly corresponds to that of sickle cell trait, thalassemia and malarial infection (10). Gilles et al. (2) reported G6PD deficiency in Negro leprosy patients in Africa. Gilles and Taylor (3) observed that 2% of Negro leprosy patients ha...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Physician Assistants
سال: 2019
ISSN: 1547-1896
DOI: 10.1097/01.jaa.0000586304.65429.a7