FvVE1 Regulates Biosynthesis of the Mycotoxins Fumonisins and Fusarins in Fusarium verticillioides

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Fumonisins, Mycotoxins Produced by Fusarium

Mycotoxins are secondary metabolites of fungi that are harmful to both animals and humans. Mycotoxicoses are diseases caused by the ingestion of foods or feeds made toxic by these fungal metabolites. Mycotoxins undoubtedly have presented a hazard to human and animal health for decades, and this threat only can become more important as the demand on the available food supply increases with the i...

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Tricarballylic ester formation during biosynthesis of fumonisin mycotoxins in Fusarium verticillioides

Fumonisins are agriculturally important mycotoxins produced by the maize pathogen Fusarium verticillioides. The chemical structure of fumonisins contains two tricarballylic esters, which are rare structural moieties and important for toxicity. The mechanism for the tricarballylic ester formation is not well understood. FUM7 gene of F. verticillioides was predicted to encode a dehydrogenase/redu...

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FvVE1 regulates filamentous growth, the ratio of microconidia to macroconidia and cell wall formation in Fusarium verticillioides.

The velvet gene, veA, co-ordinates asexual and sexual development in the homothallic fungal species Aspergillus nidulans. Studies in Aspergillus parasiticus and Aspergillus fumigatus demonstrated that veA also regulates morphological differentiation in these species. Whether veA has the same role in morphogenesis in other fungal genera has not been investigated. In this work, we studied the rol...

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HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol.

Fusarium fungi are widely found in agricultural products, worldwide and can produce a great variety of mycotoxins. Fumonisins, produced by F. moniliforme, and deoxynivalenol, produced by F. graminearum, are two such mycotoxins that have received considerable attention as food safety concerns by regulatory agencies. High Performance Liquid Chromatography/Mass Spectrometry (HPLC/MS) was found to ...

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Fumonisin mycotoxins are commonly found on maize and pose a health risk to humans and domesticated animals. Visible sorting of grain has been suggested as a simple technique that can be used to reduce exposure to fumonisins. We collected maize samples in 2003 from different farms in the Kaduna state of Nigeria (Northern Guinea Savanna agroecological zone) that had been sorted by farmers as eith...

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ژورنال

عنوان ژورنال: Journal of Agricultural and Food Chemistry

سال: 2009

ISSN: 0021-8561,1520-5118

DOI: 10.1021/jf900783u