Fungal population biology

The evolutionary biology and population genetics underlying fungal strain typing.

Strain typing of medically important fungi and fungal population genetics have been stimulated by new methods of tapping DNA variation. The aim of this contribution is to show how awareness of fungal population genetics can increase the utility of strain typing to better serve the interests of medical mycology. Knowing two basic features of fungal population biology, the mode of reproduction an...

Fungal Genetics and Biology

Manual annotation of the Phytophthora ramorum and P. sojae genomes has identified 136, and 132 members, respectively, indicating that the ABC superfamily is comparable in size to the Arabidopsis and rice genomes. The high level of synteny that was observed between these oomycete genomes extends to the ABC superfamily where 107 orthologous pairs were identified by phylogenetic analysis. The larg...

Vacuoles and fungal biology.

Fungal vacuoles have long been recognised as versatile organelles, involved in many aspects of protein turnover, cellular homeostasis, membrane trafficking, signalling and nutrition. Recent research has also revealed an expanding repertoire of physiological functions for fungal vacuoles that are vital for fungal growth, differentiation, symbiosis and pathogenesis. Vacuole-mediated long-distance...

IXth International Fungal Biology Conference &

Systems Biology of Fungal Infection

Elucidation of pathogenicity mechanisms of the most important human-pathogenic fungi, Aspergillus fumigatus and Candida albicans, has gained great interest in the light of the steadily increasing number of cases of invasive fungal infections. A key feature of these infections is the interaction of the different fungal morphotypes with epithelial and immune effector cells in the human host. Beca...