Fundamentals of Neuropathology

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منابع مشابه

[Neuropathology of frontotemporal dementia].

Frontotemporal dementia (FTD) is a clinical phenotype of dementia, characterized by complex of clinical symptoms, including disinhibition, character change, increased appetite, sexual misconduct and language problems. Frontotemporal lobar degeneration (FTLD) is a pathological classification of neurodegenerative disorder and its core consists of Pick's disease (PiD). Historically, PiD was morpho...

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Neuropathology of SUDEP

OBJECTIVE To seek a neuropathologic signature of sudden unexpected death in epilepsy (SUDEP) in a postmortem cohort by use of immunohistochemistry for specific markers of inflammation, gliosis, acute neuronal injury due to hypoxia, and blood-brain barrier (BBB) disruption, enabling the generation of hypotheses about potential mechanisms of death in SUDEP. METHODS Using immunohistochemistry, w...

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Neuropathology of Parkinsonism

The common denominator of virtually all disorders associated with clinical parkinsonism is neuronal loss in the substantia nigra, particularly of dopaminergic neurons in the pars compacta that project to the striatum (Fig. 1). The ventrolateral tier of neurons appears to be the most vulnerable in many parkinsonian disorders, and these tend to project heavily to the putamen (1). The more medial ...

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Neuropathology of mitochondrial diseases.

The term "mitochondrial diseases" (MD) refers to a group of disorders related to respiratory chain dysfunction. Clinical features are usually extremely heterogeneous because MD may involve several tissues with different degrees of severity. Muscle and brain are mostly affected, probably because of their high dependence on oxidative metabolism. Muscle can be the only affected tissue or involved ...

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Molecular Neuropathology of Gliomas

Gliomas are the most common primary human brain tumors. They comprise a heterogeneous group of benign and malignant neoplasms that are histologically classified according to the World Health Organization (WHO) classification of tumors of the nervous system. Over the past 20 years the cytogenetic and molecular genetic alterations associated with glioma formation and progression have been intense...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1954

ISSN: 0021-9746

DOI: 10.1136/jcp.7.4.355-a