Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A

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Functionalized templates for the convergent assembly of polyethers: synthesis of the HIJK rings of gymnocin A.

Extension ladder: The successful application of epoxide-opening strategies towards the synthesis of ladder-type polyethers is contingent upon further elaboration of the product. By employing two different functionalized templates, a fragment of gymnocin A that bears four sites for subsequent fragment coupling has been prepared (see scheme; Bn = benzyl).

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ژورنال

عنوان ژورنال: Angewandte Chemie International Edition

سال: 2009

ISSN: 1433-7851,1521-3773

DOI: 10.1002/anie.200900924