Functional small airways defence in symptomless cigarette smokers.
نویسندگان
چکیده
منابع مشابه
Functional small airways defence in symptomless cigarette smokers.
Smoking induced changes in the secretory cells of bronchiolar epithelium by facilitating secretion of cross linked glycoprotein mucus may influence the efficiency of mucus-cilia coupling. The functional impact on mucociliary transport in small (peripheral) airways has been studied by comparing data on aerosol deposition and clearance from symptomless cigarette smokers (30 tests, 18 subjects) wi...
متن کاملPeripheral airways function and nonspecific airways reactivity in cigarette smokers.
Increasing concentrations of inhaled aerosolized histamine acid phosphate were administered to 31 heavy cigarette smokers from a smoking cessation clinic. Nineteen of 31 smokers (mean age +/- ISD: 39.6 +/- 11.5 yrs; pack years 25.5 +/- 13.5) failed to reduce forced expired volume in one second (FEV1) while inhaling histamine and were labelled nonresponders. In 12 of 31 smokers (age 38.4 +/- 9.4...
متن کاملResponse and acclimatisation of symptomless smokers on changing to a low tar, low nicotine cigarette.
Ten symptomless smokers were switched from their usual cigarette to a low tar, low nicotine test cigarette for two weeks to investigate their immediate response and subsequent acclimatisation to the test cigarette. The tar (T) and nicotine (N) yields of the test cigarettes were T = 3.8 mg, N = 0.6 mg; the median yields of the usual cigarettes were T = 16.4 mg, N = 1.4 mg. The subjects were moni...
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CD4+CD25+ FOXP3-positive T-regulatory cells have an important role in controlling immune and inflammatory reactions. The present authors hypothesise that these cells may be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). The aim of the present study was to characterise the expression of FOXP3 in large and small airways of nonsmokers, smokers with normal lung functi...
متن کاملpersonal fable: optimistic bias in cigarette smokers
background several empirical studies have shown the attitude of smokers to formulate judgments based on distortion in the risk perception. this alteration is produced by the activation of the optimistic bias characterized by a set of the unrealistic beliefs compared to the outcomes of their behavior. this bias exposes individuals to adopt lifestyles potentially dangerous for their health, under...
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ژورنال
عنوان ژورنال: Thorax
سال: 1986
ISSN: 0040-6376
DOI: 10.1136/thx.41.7.524