Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
نویسندگان
چکیده
منابع مشابه
Transcriptional activation of DNA-dependent protein kinase catalytic subunit gene expression by oestrogen receptor-α
The cellular response to DNA double-strand break (DSB) occurs through an integrated sensing and signalling network that maintains genomic stability. Oestrogen (E2), among its many functions, is known to have a positive effect on global genomic DNA repair; however, the mechanism by which it functions is unclear. A central enzyme involved in DNA DSB repair in mammalian cells is the DNA-dependent ...
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ژورنال
عنوان ژورنال: Nature
سال: 2013
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature12210