Functional MRI

Functional MRI

In the spring of 1991 the first of a group of new methods for mapping human brain function was successfully tested at the MRI Center of the Massachusetts General Hospital, in Boston. These methods use the supremely noninvasive technique of magnetic resonance imaging to create images of the brain that are sensitive to local changes in blood flow. In identification of cortical areas active for a ...

A Primer on MRI and Functional MRI

Functional brain mapping with magnetic resonance imaging (MRI) is a rapidly growing field that has emerged in only the past several years. Functional MRI (fMRI) is the use of MRI equipment to detect regional changes cerebral metabolism or in blood flow, volume or oxygenation in response to task activation. The most popular technique utilizes blood oxygenation level dependent (BOLD) contrast, wh...

Perfusion Based Functional MRI

Evidence from functional MRI

Functional MRI (fMRI) was used to examine gender effects on brain activation during a language comprehension task. A large number of subjects (50 women and 50 men) was studied to maximize the statistical power to detect subtle differences between the sexes. To estimate the specificity of findings related to sex differences, parallel analyses were performed on two groups of randomly assigned sub...

Analysis of Functional MRI

A new information-theoretic approach is presented for analyzing fMRI data to calculate the brain activation map. The method is based on a formulation of the mutual information between two waveforms{ the fMRI temporal response of a voxel and the experimental protocol timeline. Scores based on mutual information are generated for all voxels and then used to compute the activation map of an experi...