Functional morphology and physiology of slowly adapting pulmonary stretch receptors
نویسندگان
چکیده
منابع مشابه
Lung mechanics and activity of slowly adapting airway stretch receptors.
Transpulmonary pressure is thought to be closely associated with slowly adapting mechanoreceptor activity. The transpulmonary pressure required to inflate the lung to a given volume depends on pulmonary compliance: for equal tidal volumes less pressure will be required if compliance is higher. Therefore, an inverse relationship is expected between receptor activity and lung compliance for equal...
متن کاملStructure of slowly adapting pulmonary stretch receptors in the lung periphery.
Pulmonary sensory receptors are the initiating sites for lung reflexes; however, little is known about their structure, especially the relationship between the structure and function of these receptors. Using a novel approach (combining electrophysiological and morphological techniques), we examined the structures of the typical slowly adapting pulmonary stretch receptors (SARs) located in the ...
متن کاملExcitatory mechanism of deflationary slowly adapting pulmonary stretch receptors in the rat lung.
The excitatory responses of deflationary slowly adapting pulmonary stretch receptor (SAR) activity to lung deflation ranging from approximately -15 to -25 cm of H(2)O for approximately 5 s were examined before and after administration of flecainide, a Na(+) channel blocker, and K(+) channel blockers, such as 4-aminopyridine (4-AP) and tetraethylammonium (TEA). The experiments were performed in ...
متن کاملAre neuroepithelial bodies a part of pulmonary slowly adapting receptors?
TO THE EDITOR: I would like to congratulate Adriaensen and colleagues for their excellent works that contribute to the detailed morphology of neuroepithelial bodies (NEBs) (1–3). They form a structural basis for understanding NEB physiology. A very interesting thought proposed by the authors is that NEBs may be mechanosensors. To examine this issue, we injected flourescent dye into the nodose g...
متن کاملEffects of potassium channel blockers on CO2-induced slowly adapting pulmonary stretch receptor inhibition.
In anesthetized, artificially ventilated rabbits with vagus nerve section, inhalation of CO(2) gas mixtures (tracheal CO(2) concentration ranging from 8.0 to 10.2%) for 60 s decreased slowly adapting pulmonary stretch receptor (SAR) activity during both inflation and deflation. The magnitude of decreased receptor activity during deflation had a more pronounced effect than that seen during infla...
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ژورنال
عنوان ژورنال: The Anatomical Record
سال: 2002
ISSN: 0003-276X,1097-0185
DOI: 10.1002/ar.a.10004