Functional Genomics of Odor-guided Behavior in Drosophila melanogaster
نویسندگان
چکیده
منابع مشابه
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster.
Understanding the genetic architecture of complex traits requires identification of the underlying genes and characterization of gene-by-gene and genotype-by-environment interactions. Behaviors that mediate interactions between organisms and their environment are complex traits expected to be especially sensitive to environmental conditions. Previous studies on the olfactory avoidance response ...
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The genetic toolbox in Drosophila melanogaster offers a multitude of different effector constructs to silence neurons and neuron populations. In this study, we investigated the potencies of several effector genes - when expressed in olfactory sensory neurons (OSNs) - to abolish odor-guided behavior in three different bioassays. We found that two of the tested effectors (tetanus toxin and Kir2.1...
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Previously, we generated P-element insert lines in Drosophila melanogaster with impaired olfactory behavior. One of these smell-impaired (smi) mutants, smi60E, contains a P[lArB] transposon in the second intron of the dsc1 gene near a nested gene encoding the L41 ribosomal protein. The dsc1 gene encodes an ion channel of unknown function homologous to the paralytic (para) sodium channel, which ...
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Aggressive behavior is important for animal survival and reproduction, and excessive aggression is an enormous social and economic burden for human society. Although the role of biogenic amines in modulating aggressive behavior is well characterized, other genetic mechanisms affecting this complex behavior remain elusive. Here, we developed an assay to rapidly quantify aggressive behavior in Dr...
متن کاملResources for functional genomics studies in Drosophila melanogaster.
Drosophila melanogaster has become a system of choice for functional genomic studies. Many resources, including online databases and software tools, are now available to support design or identification of relevant fly stocks and reagents or analysis and mining of existing functional genomic, transcriptomic, proteomic, etc. datasets. These include large community collections of fly stocks and p...
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ژورنال
عنوان ژورنال: Chemical Senses
سال: 2001
ISSN: 1464-3553
DOI: 10.1093/chemse/26.2.215