Functional expression and segmental localization of rat colonic K-adenosine triphosphatase.

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Functional expression and segmental localization of rat colonic K-adenosine triphosphatase.

A putative cDNA for the colonic K-ATPase has recently been cloned (Crowson, M.S., and G. E. Shull. 1992. J. Biol. Chem. 267:13740-13748). Considerable evidence exists that there are two K-ATPases and active K absorptive processes in the rat distal colon: one that is ouabain sensitive and the other ouabain insensitive. The present study used the baculovirus expression system to express K-ATPase ...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1995

ISSN: 0021-9738

DOI: 10.1172/jci118247