Functional effects of KCNQ K+ channels in airway smooth muscle

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Functional effects of KCNQ K+ channels in airway smooth muscle

KCNQ (Kv7) channels underlie a voltage-gated K(+) current best known for control of neuronal excitability, and its inhibition by Gq/11-coupled, muscarinic signaling. Studies have indicated expression of KCNQ channels in airway smooth muscle (ASM), a tissue that is predominantly regulated by muscarinic receptor signaling. Therefore, we investigated the function of KCNQ channels in rodent ASM and...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2013

ISSN: 1664-042X

DOI: 10.3389/fphys.2013.00277