Fumonisin B1 Increases Serum Sphinganine Concentration but Does Not Alter Serum Sphingosine Concentration or Induce Cardiovascular Changes in Milk-Fed Calves
نویسندگان
چکیده
منابع مشابه
Serum Biochemistry, Lipid and Pathology Alterations in Sinclair Minipigs Fed Low Levels of Fumonisin B1 for Six Months. Introduction Fumonisins are a group of naturally occurring mycotoxins produced by the fungus Fusarium verticillioides
Fumonisins are a group of naturally occurring mycotoxins produced by the fungus Fusarium verticillioides (previously moniliforme). Fumonisin B1 (FB1), is the most common toxin produced. Fumonisins alter sphingolipid biosynthesis, induce hepatotoxicity, and elevate serum cholesterol concentration in all species studied including pigs, calves, lambs, mice, rats, mink, and broiler chicks. A major ...
متن کاملPurified fumonisin B(1) decreases cardiovascular function but does not alter pulmonary capillary permeability in swine.
Fumonisins are mycotoxins produced by Fusarium verticillioides, which induce acute pulmonary edema in swine. We previously reported that ingestion of fumonisin-containing culture material decreases cardiovascular function in swine (1996,a,b; Fundam. Appl. Toxicol. 31, 169-172; 33, 140-148; 1999, Am. J Vet. Res. 60, 1291-1300). The main purpose of this study was to confirm that fumonisin B(1) wa...
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Sphingosine 1-phosphate (S1P) is a lipid mediator formed by the metabolism of sphingomyelin which is involved in the endothelial permeability and inflammation. Although the plasma S1P concentration is reportedly decreased in patients with cerebral malaria, the role of S1P in malaria is still unclear. The purpose of this study was to examine the impact of malaria on circulating S1P concentration...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2001
ISSN: 1096-0929
DOI: 10.1093/toxsci/60.2.379