Full-length recombinant choline transporter-like protein 2 containing arginine 154 reconstitutes the epitope recognized by HNA-3a antibodies
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چکیده
منابع مشابه
Identification of the HNA-3a antigen.
Among the 5 HNA systems, HNA-3 was the only one that had yet to be characterized. This effort was critical because antibodies directed to HNA-3a are responsible for causing numerous cases of transfusion-related acute lung injury (TRALI), especially fatal TRALI.2-4 Antibodies to HNA-3a cause neutrophil (PMN) agglutination, priming of the PMN oxidase, and PMN-mediated killing of pulmonary endothe...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2011
ISSN: 0041-1132
DOI: 10.1111/j.1537-2995.2011.03411.x