Frontotemporal dementia, music perception and social cognition share neurobiological circuits: A meta-analysis

Social Cognition and Emotional Assessment differentiates frontotemporal dementia from depression.

BACKGROUND Behavioural variant of frontotemporal dementia (bvFTD) is a neurodegenerative disease that is clinically characterised by progressive behavioural changes and social interpersonal dysfunctions. Its diagnosis remains a clinical challenge, and depression is one of the main causes of misdiagnoses due to the prevalence of apathy in bvFTD. OBJECTIVE To evaluate the sensitivity and specif...

Music, reward and frontotemporal dementia

Sir, The recent study by Perry et al. (2014) draws attention to the important issue of abnormally enhanced reward-seeking by patients with frontotemporal dementia (FTD). This issue presents major challenges for the clinical management of these patients and provides a unique window on the neurobiology of brain network disintegration in a diverse group of neurodegenerative pathologies. While Perr...

Mentalising music in frontotemporal dementia

Despite considerable recent interest, the biological basis and clinical diagnosis of behavioural variant frontotemporal dementia (bvFTD) pose unresolved problems. Mentalising (the cognitive capacity to interpret the behaviour of oneself and others in terms of mental states) is impaired as a prominent feature of bvFTD, consistent with involvement of brain regions including ventro-medial prefront...

Music Perception and Cognition

Music perception and cognition is the area of cognitive psychology devoted to determining the mental mechanisms underlying our appreciation of music, and in this chapter we review the major findings. We begin with the perception and cognition of pitch, which is the most thoroughly researched area in the field. We then consider perceptual organization in music in the dimension of time, followed ...

Music Perception and Cognition