Frequency of Rare Bleeding Disorders
نویسندگان
چکیده
Objective: The incidence and range of rare hereditary bleeding diseases, as well the severity deficiency its many clinical presentations, were subjects our study. Study Design: Cross-sectional study Place Duration: Department Pathology, Northwest School Medicine Peshawar in duration from July, 2022 to December, 2022. Methods: Total 850 cases coagulation disorders presented this A thorough demographic analysis recruited was done after receiving informed written consent. After taking note symptoms indicators, a profile used diagnose patients. With use factor tests, illness evaluated. All data examined using SPSS 23.0. Results: Among cases, 113 (13.3%) patients had disorders. In disorders, there majority 70 (61.9%) males 43 (38.1%) females. Mean age 10.5±13.69 years. 47 (41.6%) urban areas 66 (58.4%) rural residency. Most common VII found 33 (29.2%) followed by fibrinogen 22 (19.5%) cases. 17 (15.04%) family history bleeding. Frequency consanguinity 88 (77.9%) symptom bruising, gum bleeding, epistaxis menorrhagia. Conclusion: We concluded higher frequency 13.3% Factor is most typical uncommon condition community. Due high rate consanguineous marriages society, these diseases are very common. Keywords: deficiency, Rare assay, Consanguinity
منابع مشابه
Rare bleeding disorders.
During the haemostatic response, the formation of a primary platelet plug limits bleeding and provides a surface for clotting factors to assemble and become activated. The initial platelet plug is stabilized by fibrin monomers, covalently cross-linked by FXIII, forming a platelets-fibrin thrombus. Defects in platelets as well as inherited deficiencies of coagulation factors including fibrinogen...
متن کاملRare bleeding disorders: diagnosis and treatment.
Despite the worldwide prevalence of rare bleeding disorders (RBDs), knowledge of these conditions and their management is suboptimal; health care professionals often have little diagnostic and treatment experience with variable access to diagnostic modalities required for accurate identification. Therefore, patients often experience morbidity and mortality due to delayed diagnosis. As RBDs repr...
متن کاملRare Bleeding Disorders in Children: Identification and Primary Care Management
Bleeding symptoms are common in healthy children but occasionally may indicate an underlying congenital or acquired bleeding diathesis. The rare bleeding disorders (RBDs) comprise inherited deficiencies of coagulation factors I (congenital fibrinogen deficiencies), II, V, VII, X, XI, and XIII and combined factor deficiencies, most notably of factors V and VIII and of vitamin K–dependent factors...
متن کاملRare bleeding disorders: genetic, laboratory, clinical, and molecular aspects. Preface.
Welcome to this special issue of Seminars in Thrombosis & Hemostasis. Characteristically, each issue of Seminars in Thrombosis & Hemostasis is theme driven, with each new issue devoted to a particular theme of relevance to thrombosis and hemostasis. The current issue of Seminars in Thrombosis & Hemostasis carries the theme of “Rare Bleeding Disorders” (RBDs) and is an update on a previous issue...
متن کاملRare Bleeding Disorders: Genetic, Laboratory, Clinical, and Molecular Aspects
Welcome to this special issue of Seminars in Thrombosis & Hemostasis. Characteristically, each issue of Seminars in Thrombosis & Hemostasis is theme driven, with each new issue devoted to a particular theme of relevance to thrombosis and hemostasis. The current issue of Seminars in Thrombosis & Hemostasis carries the theme of “Rare Bleeding Disorders” (RBDs) and is an update on a previous issue...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pakistan Journal of Medical and Health Sciences
سال: 2023
ISSN: ['1996-7195']
DOI: https://doi.org/10.53350/pjmhs2023174569