Frequency of G2677T/A and C3435T polymorphisms of MDR1 gene in preeclamptic women
نویسندگان
چکیده
منابع مشابه
Frequency of G2677T/A and C3435T polymorphisms of MDR1 gene in preeclamptic women.
OBJECTIVE Preeclampsia (PE) belongs to main causes of mortality rates of mothers, fetuses and new born children. Polymorphism of MDR1 gene is connected with reduction of P-glycoprotein expression in placenta and increased fetal exposure to xenobiotics. The aim of the study was to determine the frequency of C3435T and G2677T/A polymorphisms of MDR1 gene in pregnant women with preeclampsia. MAT...
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The multi-drug resistance 1 (MDR1) gene encodes for a P-glycoprotein (PGP), which acts as a gate-keeper against various kinds of xenobiotics. Several single nucleotide polymorphisms (SNPs) in the MDR1 gene that may influence PGP level and function have been identified. The aim of this study was to simultaneously analyze the three most important MDR1 SNPs, C3435T, G2677T/A and C1236T, in the Ser...
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15 صفحه اولFrequency of the Mdr1 Gene Polymorphism Rs1045642 (c3435t) in Hcv-hiv Co-infected Patients.
Background Due to the high prevalence of co-infection by hepatitis C virus (HCV) and human immunodeficiency virus (HIV) and the severity of these infections, the understanding of the biological mechanisms involved in these processes, including viral behavior and host genetic profile, is of great importance for patient treatment and for public health policies.Some single nucleotide polymorphisms...
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ژورنال
عنوان ژورنال: Polish Gynaecology
سال: 2013
ISSN: 0017-0011
DOI: 10.17772/gp/1640