Frequency of antigen-specific B cells during experimental ocular Chlamydia trachomatis infection

P-204: Relative Frequency of Chlamydia Trachomatis Infection in Infertile Women

Background: The majority of Chlamydia trachomatis infections in women are asymptomatic, but they may give rise to tubal infertility. Screening programmes aim at reducing morbidity in individual by early detect and treatment, and at decreasing the overall prevalence of infection in the population. Materials and Methods: A total of 135 women presenting with a history of infertility(n=113(83.7%) p...

Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection.

Chlamydia trachomatis is an obligate intracellular bacterium that causes a variety of diseases in humans. C. trachomatis has a complex developmental cycle that depends on host cells for replication, during which gene expression is tightly regulated. Here we identify two C. trachomatis proteases that possess deubiquitinating and deneddylating activities. We have designated these proteins ChlaDub...

Infection Modulates Chlamydia trachomatis

P-59: Chlamydia Trachomatis Infection in Femaleswith Secondary Infertility

Background: We designed a prospective study to assess the role of Chlamydia in secondary infertility Materials and Methods: 40 women with secondary infertility and 30 term healthy pregnant women of similar age composition were studied for past and present chlamydia trachomatis infection. Women attending the outpatient department of Obstetrics and Gynaecology with complaint of secondary infertil...

Experimental Chlamydia trachomatis infection causes apoptosis in human sperm.

BACKGROUND Chlamydia trachomatis is responsible for a widespread sexually transmitted infection. In men, it is associated with a wide clinical spectrum causing infertility. Furthermore, C. trachomatis serovar E infection decreases motility and increases the number of non-viable sperm. No other effects of C. trachomatis have been reported on sperm despite the crucial role of DNA integrity for sp...