FOXP3, RORγt and IL-10 cytokine profile in chronic heart failure
نویسندگان
چکیده
منابع مشابه
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
The nuclear hormone receptor retinoic acid receptor-related orphan receptor gamma t (RORgamma t) is required for the generation of T helper 17 cells expressing the proinflammatory cytokine interleukin (IL)-17. In vivo, however, less than half of RORgamma t(+) T cells express IL-17. We report here that RORgamma t(+) T alphabeta cells include Foxp3(+) cells that coexist with IL-17-producing RORga...
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BACKGROUND The participation of immune/inflammatory mechanisms in the pathogenesis of tropical endomyocardial fibrosis (EMF) has been suggested by the finding of early blood and myocardial eosinophilia. However, the inflammatory activation status of late-stage EMF patients is still unknown. METHODOLOGY/PRINCIPAL FINDINGS We evaluated pro- and anti-inflammatory cytokine levels in plasma sample...
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ژورنال
عنوان ژورنال: Bratislava Medical Journal
سال: 2018
ISSN: 1336-0345
DOI: 10.4149/bll_2017_122