Formulation development and investigation of domperidone transdermal patches
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Matrix Diffusion Controlled Transdermal Patches of Domperidone hydrochloride
Objective: To quantify, to value and to analyze the pharmacological interactions in the patients who come to a community pharmacy. Method: Cross-sectional study of one year in a community pharmacy of Valencia. The interactions were detected by the program BotPlus of the General Council of Pharmacists’ Official Colleges. Results: 63,64 % of the interactions took place in women. More than 63 % ap...
متن کاملDevelopment of domperidone bilayered matrix type transdermal patches: physicochemical, in vitro and ex vivo characterization
BACKGROUND AND THE PURPOSE OF THE STUDY Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, which is widely used in the treatment of motion-sickness. The pharmacokinetic parameters make DOM a suitable candidate for transdermal delivery. The purpose of the present investigation was to develop transdermal delivery systems for DOM and to evaluate their physicochemical characteristics, in ...
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Losartan potassium is a well known orally active non-peptide angiotensin II receptor antagonist. Losartan potassium and its principle active metabolites block the vasoconstrictor and aldosterone secreting effect of angiotensin II by selectively blocking the binding of angiotensin II to AT1 receptors. The drug is reported to promote the decrease in ventricular hypertrophy, salt ...
متن کاملFormulation and Evaluation of Transdermal Patches of Glizpizide
Drug Delivery through skin would provide a useful alternative to oral delivery, which has numerous side effects. Therefore, the present investigation was aimed to develop sustained release transdermal therapeutics system containing Glipizide with varying ratios of HPMC & PVPK30 using solvent evaporation technique. Ten different formulations were prepared keeping the concentration of Glipizide c...
متن کاملDevelopment and evaluation of carvedilol transdermal patches.
Transdermal patches of carvedilol with a HPMC-drug reservoir were prepared by the solvent evaporation technique. In this investigation, the membranes of Eudragit RL100 and Eudragit RS100 were cast to achieve controlled release of the drug. The prepared patches possessed satisfactory physicochemical characteristics. Thickness, mass and drug content were uniform in prepared batches. Moisture vapo...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Investigation
سال: 2011
ISSN: 2230-973X
DOI: 10.4103/2230-973x.93008