FORMULATION AND EVALUATION OF FLOATING ORAL IN SITU GEL OF DILTIAZEM HYDROCHLORIDE
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Floating Gastroretentive Drug Delivery System of Diltiazem Hydrochloride
The present investigation describes the design and evaluation of monolithic gastro retentive dosage forms of diltiazem. Hydrophilic cellulose derivatives, Sodium alginate, Sodium carboxy methyl cellulose, Polyox, Methocel K100M in combination with Methocel E6LV are used as the rate controlling polymers. Sodium bicarbonate was incorporated as gas generating agent. Tablets were prepared by employ...
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Tizanidine hydrochloride is an orally administered prokinetic agent that facilitates or restores motility through-out the length of the gastrointestinal tract. The objective of the present investigation was to develop effervescent floating matrix tablets of tizanidine hydrochloride for prolongation of gastric residence time in order to overcome its low bioavailability (34-40 %) and short biolog...
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To develop a multi-unit gastroretentive sustained release dosage form of a water-soluble drug, Verapamil hydrochloride, from a completely aqueous environment. avoiding the use of any organic solvent, thus releasing the drug for a prolonged duration of time. Emulsion gelation technique was used to prepare emulsion gel beads using sodium alginate as the polymer. The gel beads containing oil was p...
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Purpose. Effective Helicobacter pylori eradication requires delivery of the antibiotic locally in the stomach. High dose of amoxicillin (750 to 1000 mg) is difficult to incorporate in floating tablets but can easily be given in liquid dosage form. Keeping the above facts in mind, we made an attempt to develop a new floating in situ gelling system of amoxicillin with increased residence time usi...
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Cervicofacial hemangiomas treated from January 2001 to December 2009 was clinically evaluated. This retrospective clinical study consisted of 42 females and 20 males with the age ranged from 20 days to 55 years. The lesions were present with-in first month in 45 patients (72.6%). Two patterns of tumor growth were evident: focal and diffuse. There were 59 focal hemangiomas (80.8%) and 14 diffuse...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2016
ISSN: 0975-7058
DOI: 10.22159/ijap.2017v9i1.15914