FORMULATION AND EVALUATION OF FAMOTIDINE FLOATING MICROSPONGES
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Floating Drug Delivery System of Famotidine
A multiple unit oral floating drug delivery system of famotidine was developed to prolong gastric residence time, target stomach mucosa and increase drug bioavailability. Drug and polymer compatibility was studied by subjecting physical mixtures of drug and polymers to differential scanning calorimetry. Cod liver oil entrapped calcium alginate beads containing famotidine, capable of floating in...
متن کاملFormulation and Evaluation of Effervescent Floating Tablet of Famotidine
Famotidine has been the most widely used drug for the treatment of peptic ulcer for many decades. The present investigation concerns the development and evaluation of floating tablets of famotidine which, after oral administration, are designed to prolong the gastric residence time, increase drug bioavailability and target the gastric ulcer. A floating drug delivery system (FDDS) was developed ...
متن کاملFormulation and in Vitro - in Vivo Evaluation of Bilayer Floating- Bioadhesive Famotidine Tablets
Bilayer floating-bioadhesive drug delivery systems exhibiting a unique combination of floatation and bioadhesion to prolong gastric residence time were developed. Hydroxypropyl methylcellulose and sodium bicarbonate were added such that when immersed in 0.1N HCl, the tablet expands and rises to the surface and famotidine is gradually released without interference from gas bubbles. Effect of dif...
متن کاملFormulation and in Vitro Evaluation of Famotidine Floating Tablets by Lipid Solid Dispersion Spray Drying Technique
The purpose of this investigation was to prepare a gastro retentive drug delivery system of famotidine tablets. Floating tablets of famotidine were prepared employing lipid solid dispersion spray drying technique with gelucire 50/13 and compritol 888 along with HPMC K100M, lactose, sodium bicarbonate and citric acid. The floating tablets were evaluated for uniformity of weight, hardness, friabi...
متن کاملFormulation and evaluation of effervescent floating tablet of famotidine with natural polymer chitosan
A Novel floating controlled release drug delivery system of famotidine was formulated in an effort to increase the gastric retention time of the dosage form and to control drug release. The present work investigates the approach using two different polymers HPMC K100 M and natural polymer Chitosan . A floating drug delivery system (FDDS) was developed using gas-forming agents, like sodium bicar...
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ژورنال
عنوان ژورنال: International Research Journal of Pharmacy
سال: 2016
ISSN: 2230-8407
DOI: 10.7897/2230-8407.07440