Formula for the estimation of urine osmolality in healthy cats

A simple and intuitive formula for the estimation of urine osmolality (Uosm) using measured concentrations major active osmolytes over a wide range dilutions was proposed in healthy cats. Sixty-three samples were retrieved ultrasound-guided cystocentesis from sixteen cats under 5 years age receiving intravenous infusion period 24 h. Samples collected at baseline (T0), T2, T6, T12, T24. Urine freezing-point osmometer, (urea, sodium, glucose, potassium) evaluated. linear regression model clinical use selected, agreement between calculated actual osmolalities assessed. Urinary urea, sodium glucose three variables included with lowest AICC. can be predicted accurately precisely following equation: Uosm = 1.25 × urea (mmol/l) or 20.87 (g/l) + 1.1 67 3.72 (mg/dl). The concordance correlation coefficient repeated measures extremely close to 1, which supported high agreement: 0.996 (CI 95%: [0.993; 0.998]). In population cats, urinary concentrations. Similar formulae could potentially established help clinician pathological situations.