Forebrain elimination of cacna1c mediates anxiety-like behavior in mice
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چکیده
منابع مشابه
Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice.
Although numerous stress-related molecules have been implicated in vulnerability to psychiatric illness, especially major depression and anxiety disorders, the role of the brain mineralocorticoid receptor (MR) in stress, depression, and affective function is not well defined. MR is a steroid hormone receptor that detects circulating glucocorticoids with high affinity and has been primarily impl...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2012
ISSN: 1359-4184,1476-5578
DOI: 10.1038/mp.2012.71