منابع مشابه
Forces driving epithelial wound healing
A fundamental feature of multicellular organisms is their ability to self-repair wounds through the movement of epithelial cells into the damaged area. This collective cellular movement is commonly attributed to a combination of cell crawling and "purse-string" contraction of a supracellular actomyosin ring. Here we show by direct experimental measurement that these two mechanisms are insuffici...
متن کاملCorneal epithelial wound healing.
The corneal surface is, without question, the most specialised 123 mm2* of the body's surface. It forms an integral part of the ocular surface with which it shares several anatomical and physiological attributes. Like the rest ofthe body surface, it is in a state of constant 'healing'. Squamous epithelial cells are continually shed into the tear pool and simultaneously replenished by cells movi...
متن کاملConjunctival epithelial wound healing.
In vivo conjunctival epithelial healing in albino rabbits was investigated by light microscopy following both n-heptanol and trephined conjunctival wounding. Reepithelialization occurred faster following n-heptanol treatment (3 days) versus trephination (6-7 days). No goblet cells were present in the migrating epithelium during reepithelialization. After 1 day of wounding, goblet cells disappea...
متن کاملEpithelial Regeneration and Wound Healing
SAINT in 1929 documented the experimental studies that had been carried out up to that date on the healing of oesophageal wounds. The reported observations dealt with the relatively long-term results, and little attention was paid to the early changes that occurred during the period immediately following the infliction of the wound. Recently, Malm (1951) made observations following surgical exp...
متن کاملInfluence of defunctionalization and mechanical forces on intestinal epithelial wound healing.
The influence on mucosal healing of luminal nutrient flow and the forces it creates are poorly understood. We hypothesized that altered deformation and extracellular pressure mediate, in part, the effects of defunctionalization on mucosal healing. We created patent or partially obstructing defunctionalizing jejunal Roux-en-Y anastomoses in rats to investigate mucosal healing in the absence or p...
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ژورنال
عنوان ژورنال: Nature Physics
سال: 2014
ISSN: 1745-2473,1745-2481
DOI: 10.1038/nphys3040