Follow-up younger patient with anti-NMDA-R encephalitis

نویسندگان

چکیده

Case presentation: Male, 8 months old, previously healthy, initiated with fever, inappetence, dystonia and axial hypotonia. Initial examination presented cerebrospinal fluid (CSF) lymphomononuclear leukocytosis proteinorrachia. Electroencephalogram (EEG) slowed base activity. Other infectious screening tests viral serology, rheumatological, neoplastic diseases, nuclear magnetic resonance (NMR) imaging of the brain were standard. After exclusion main causes encephalitis, antibodies against N-methyl-D-aspartate receptor (NMDA-R) identified in CSF. It evolved worsening motor respiratory, regression neuropsychomotor development (NPMD), he needed tracheostomy (TQT) gastrostomy (G-tube). Treatment, besides a front line steroids Human Immunoglobulin, six cyclophosphamide cycles starting azathioprine, remaining hospitalized for four months. Following up, at five years age, is still using weaning. He presents NPMD milestones appropriate his chronological age. There no need

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ژورنال

عنوان ژورنال: Arquivos De Neuro-psiquiatria

سال: 2023

ISSN: ['1678-4227', '0004-282X']

DOI: https://doi.org/10.1055/s-0043-1774630