منابع مشابه
Folate bioavailability.
The achievement of optimal folate status to prevent neural-tube defects, and possibly other diseases, is hindered by the well-recognised incomplete bioavailability of the natural folates found in foods compared with the synthetic vitamin, folic acid. Folate bioavailability from different foods is considered to be dependent on a number of factors, including the food matrix, the intestinal deconj...
متن کاملEffect of paternal folate deficiency on placental folate content and folate receptor α expression in rats
We investigated the effect of paternal folate status on folate content and expression of the folate transporter folate receptor α (FRα) in rat placental tissues. Rats were mated after males were fed a diet containing 0 mg of folic acid/kg of diet (paternal folate-deficient, PD) or 8 mg folic acid/kg of diet (paternal folate-supplemented, PS) for 4 weeks. At 20 days of gestation, the litter size...
متن کاملFolate absorption
Folic acid, or pteroylglutamic acid, is the parent substance of a large group of related compounds called 'folates'. All folate compounds have the same basic molecular structure consisting of three parts: pteridine, para-aminobenzoate (these two together forming a pteroyl group), and L-glutamic acid (Fig. 1). Pteroylglutamic acid itself is a stable, watersoluble compound with a molecular weight...
متن کاملPlasma and erythrocyte folate in iron deficiency and folate deficiency.
I T WAS SHOWN by Toennies et a!.1 that most of the blood folate is within the erythrocytes. The erythrocyte folate level may be reduced in either folate or vitamin B12 deficiency,25 and it can be used as an index of the folate content of body tissues.4 The present paper reports that in iron deficiency anemia there are abnormalities in distribution of folate between plasma and erythrocytes which...
متن کاملImpact Of Folate Depletion On Expression Of Folate Metabolizing Enzymes
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ژورنال
عنوان ژورنال: Advances in Nutrition
سال: 2013
ISSN: 2156-5376,2161-8313
DOI: 10.3945/an.112.003392