منابع مشابه
Oestrogens, Progestins and Combinations
'Steroid hormones are essential for the growth, differentiation and function of many tissues in both animaIs and humans. It has been established by animal experimentation that modification of the hormonal environment by surgical removal of endocrine glands, by pregnancy or by exogenous administration of steroids can increase or decrease the spontaneous occurrence of tumours or the induction of ...
متن کاملOestrogens and the skin.
Oestrogen loss at the menopause has a profound influence on skin. Oestrogen treatment in post-menopausal women has repeatedly been shown to increase collagen content, dermal thickness and elasticity. Data on the effect of oestrogen on skin water content are also promising. Further, physiological studies on oestrogen and wound healing suggest that hormone replacement therapy (HRT) may play a ben...
متن کاملOestrogens and spermatogenesis.
The role of oestrogens in male reproductive tract physiology has for a long time been a subject of debate. The testis produces significant amounts of oestrogenic hormones, via aromatase, and oestrogen receptors (ERs)alpha (ESR1) and ERbeta (ESR2) are selectively expressed in cells of the testis as well as the epididymal epithelium, depending upon species. This review summarizes the current know...
متن کاملOestrogens and Mammary Carcinogenesis
There is a large and compelling body of epidemiological and experimental evidence that oestrogens are the fuel behind the aetiology of breast cancer. The carcinogenic effects of oestrogen are postulated to be mediated by: the stimulation of cellular proliferation through their receptor-mediated hormonal activity. Other mechanisms include; direct genotoxic effects by increasing mutation rates th...
متن کاملOestrogens and postprandial lipid metabolism.
Introduction Oestrogens protect against coronary artery disease (CAD) [l-31. An estimated 2540% of this protective effect can be attributed to changes in fasting plasma lipids [4]. Low-density lipoprotein (LDL) cholesterol concentrations are reduced [5,6] as the result of enhanced clearance of atherogenic LDL particles by upregulated LDL receptors [7,8]. The production of highdensity lipoprotei...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2019
ISSN: 1359-4184,1476-5578
DOI: 10.1038/s41380-019-0454-9