Fluoroquinolones Reported Hepatotoxicity
نویسندگان
چکیده
منابع مشابه
Herbal hepatotoxicity: a tabular compilation of reported cases.
BACKGROUND Herbal hepatotoxicity is a field that has rapidly grown over the last few years along with increased use of herbal products worldwide. AIMS To summarize the various facets of this disease, we undertook a literature search for herbs, herbal drugs and herbal supplements with reported cases of herbal hepatotoxicity. METHODS A selective literature search was performed to identify pub...
متن کاملTraditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases
Traditional Chinese Medicine (TCM) with its focus on herbal use became popular worldwide. Treatment was perceived as safe, with neglect of rare adverse reactions including liver injury. To compile worldwide cases of liver injury by herbal TCM, we undertook a selective literature search in the PubMed database and searched for the items Traditional Chinese Medicine, TCM, Traditional Asian Medicin...
متن کاملPharmacodynamics of fluoroquinolones.
Fluctuating concentrations of three fluoroquinolones (moxifloxacin, sparfloxacin and ofloxacin) and a beta-lactam (amoxycillin) were used in vitro to simulate antibiotic concentrations in human serum after oral doses of antibiotics. The antibiotics were tested against Staphylococcus aureus 12241 and Streptococcus pneumoniae 4241. Moxifloxacin and sparfloxacin were also tested against Escherichi...
متن کاملAntitrypanosomal activity of fluoroquinolones.
Six fluoroquinolones presently in clinical use and four investigational tetracyclic fluoroquinolones were tested for in vitro activity against bloodstream-form Trypanosoma brucei brucei. All compounds had measurable activity, but the tetracyclic analogs were most potent, with 50% effective concentrations in the low micromolar range. In general, trypanosomes were more susceptible than L1210 leuk...
متن کاملAn Overview of Fluoroquinolones
22 The fluoroquinolones are broad-spectrum bactericidal agents inhibiting DNA 23 synthesis. They are active against gram positive and gram negative organisms like P. 24 aeruginosa, Mycoplasma, Chlamydia, Staphylococci and a few of the Streptococci. They are 25 useful in the treatment of pneumonia, urinary tract infections, bacterial diarrhea, and skin and 26 soft tissue infections. The use of q...
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ژورنال
عنوان ژورنال: Pharmacology & Pharmacy
سال: 2012
ISSN: 2157-9423,2157-9431
DOI: 10.4236/pp.2012.33044