Fluid Resuscitation for Refractory Hypotension

Permissive Hypotension Strategies for the Far-Forward Fluid Resuscitation of Significant Hemorrhage1

Acute hemorrhage accounts for about 50% of the deaths on the battlefield in conventional warfare. In addition, hemorrhage is the primary cause of death in 30% of injured soldiers who die from wounds. With future combat strategies focused around the Objective Force Warrior, greater dispersal of troops and fighting in urban settings and on non-linear battlefields, the likelihood of longer evacuat...

REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): study protocol for a pilot randomised controlled trial

BACKGROUND Guidelines recommend an initial intravenous (IV) fluid bolus of 30 ml/kg isotonic crystalloid for patients with sepsis and hypotension. However, there is a lack of evidence from clinical trials to support this. Accumulating observational data suggest harm associated with the injudicious use of fluids in sepsis. There is currently equipoise regarding liberal or restricted fluid-volume...

Vasopressin for refractory hypotension during cardiopulmonary bypass.

Colloids in Dialytic Refractory Hypotension

Colloid solutions for fluid resuscitation.

BACKGROUND Colloids are widely used in the replacement of fluid volume. However doubts remain as to which colloid is best. Different colloids vary in their molecular weight and therefore in the length of time they remain in the circulatory system. Because of this and their other characteristics, they may differ in their safety and efficacy. OBJECTIVES To compare the effects of different collo...