FLIPR: A New Instrument for Accurate, High Throughput Optical Screening
نویسندگان
چکیده
منابع مشابه
High-throughput screening for Kv1.3 channel blockers using an improved FLIPR-based membrane-potential assay.
Voltage-gated K(+) channels are potential drug targets for an increasing number of disease indications. Searching for compounds that modulate K(+) channel activities by high-throughput screening (HTS) is becoming a standard approach in the drug discovery effort. Here the authors report an improved fluorometric imaging plate reader (FLIPR) membrane potential assay for Kv1.3 K(+) channel HTS. The...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 1996
ISSN: 1087-0571,1552-454X
DOI: 10.1177/108705719600100205