FLASH Meets Nuclear Bodies: CD95 Receptor Signals via a Nuclear Pathway
نویسندگان
چکیده
منابع مشابه
FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies.
Caspase-8-binding protein FLICE-associated huge protein (FLASH) has been proposed to regulate death receptor CD95-induced apoptosis through facilitating caspase-8 activation at the death-inducing signaling complex. Here, we found that FLASH interacts with the PML nuclear body component Sp100 and predominantly resides in the nucleus and nuclear bodies (NBs). In response to CD95 activation, FLASH...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2007
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.6.7.4046