Flagellation of Salmonella typhimurium Treated with Nalidixic Acid

Ubiquinone synthetic pathway in flagellation of Salmonella typhimurium.

Flagellation of Salmonella typhimurium was found to require a functional pathway for ubiquinone synthesis as well as growth in the presence of aliphatic or aromatic carboxylic acids. Selection for constitutive flagellation eliminated the requirement for growth in the presence of added carboxylic acids.

Nalidixic acid for enrichment of auxotrophs in cultures of Salmonella typhimurium.

Nalidixic acid kills only growing cells of Salmonella typhimurium and can be used to enrich for auxotrophs in populations where prototrophs predominate.

Positive adaptive state: microarray evaluation of gene expression in Salmonella enterica Typhimurium exposed to nalidixic acid.

The emergence of antimicrobial resistance among foodborne bacteria associated with food animal production is an important global issue. We hypothesised that antibiotics generate a positive adaptive state in Salmonella that actively contributes to the development of antimicrobial resistance. This is opposed to common views that antimicrobials only act as a passive selective pressure. Microarray ...

Isolation and characterization of FliK-independent flagellation mutants from Salmonella typhimurium.

A flagellum of Salmonella typhimurium and Escherichia coli consists of three structural parts, a basal body, a hook, and a filament. Because the fliK mutants produce elongated hooks, called polyhooks, lacking filament portions, the fliK gene product has been believed to be involved in both the determination of hook length and the initiation of the filament assembly. In the present study, we iso...

nalidixic acid-resistant Salmonella enterica serotype Paratyphi A