Fixation of Transparent Bone Pins with Photocuring Biocomposites

Bone fractures are in need of rapid fixation methods, but the current strategies limited to metal pins and screws, which necessitate secondary surgeries upon removal. New techniques sought avoid surgical revisions, while maintaining or improving speed. Herein, a method bone is proposed with transparent biopolymers anchored place via light-activated biocomposites based on expanding CaproGlu bioadhesives. The serve as UV light guide for activation biocomposites, results evolution molecular nitrogen (from diazirine photolysis), simultaneously covalently cross-linked matrix. Osseointegration additives hydroxyapatite Bioglass 45S5 yield biocomposite matrix increased stiffness pullout strength. structure-property relationships joules dose, pin diameter, assessed respect apparent viscosity, shear modulus, spatiotemporal curing, lap-shear adhesion. Finally, model system ex vivo investigation tissue exploration optimization UV-active biopolymer fixation.