Fission Yeast Does Not Age under Favorable Conditions, but Does So after Stress

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Fission Yeast Does Not Age under Favorable Conditions, but Does So after Stress

BACKGROUND Many unicellular organisms age: as time passes, they divide more slowly and ultimately die. In budding yeast, asymmetric segregation of cellular damage results in aging mother cells and rejuvenated daughters. We hypothesize that the organisms in which this asymmetry is lacking, or can be modulated, may not undergo aging. RESULTS We performed a complete pedigree analysis of microcol...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2013

ISSN: 0960-9822

DOI: 10.1016/j.cub.2013.07.084